阿滋海默症的新發現 -- TNF --
Reversal Of Alzheimer's Symptoms Within Minutes In Human Study Annotated
tags: alzheimer, dementia- 新一期的神經發炎期刊發表此一在科學上屬相當非凡的發現:“Rapid cognitive improvement in Alzheimer’s disease following perispinal etanercept administration,” and the accompanying commentary, entitled “Perispinal etanercept: Potential as an Alzheimer’s therapeutic,”
- 此 研究顯示某些稱作Cytokines的水溶性蛋白質在阿茲海默疾病的重要性,其中一種,TNF,是腦免疫系統極為重要的一員,此蛋白質精密的調節腦內神經 衝動的傳遞,研究人員假設阿茲海默疾病中,高濃度的TNF會干擾此調節系統,因此作者給病人注射一種抗TNF的治療劑,稱作Eanercept,來降低 TNF的濃度。在阿茲海默病病患者的腦脊液中證實有是高濃度的TNF-alpha。患者經由脊椎注射Etanercept後,出現數分鐘的進步。
- Anti-TNF治療劑,Etanercept,已成為許多疾病的新治療方式,如類風濕性關節炎,甚至是阿茲海默病,此藥物最近被哈佛健康信息選為2007年前十大健康新聞。
Reversal Of Alzheimer's Symptoms Within Minutes In Human Study
ScienceDaily (Jan. 9, 2008)— An extraordinary new scientific study, which for the first time documents marked improvement in Alzheimer’s disease within minutes of administration of a therapeutic molecule, has just been published in the Journal of Neuroinflammation.
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